Hughes Syndrome is now recognised as a major 'new' disease. It has been described by colleague Dr Josep Font of Barcelona, as, "one of the two new diseases (with AIDS) of the 20th century". The messages are simple. Blood clots can cause untold damage. The tendency to 'sticky blood' found in Hughes Syndrome can be diagnosed by simple blood tests. The use of medicines, some as simple as aspirin, can protect against the clotting tendency. Kay Thackray here provides just the sort of clear guidance patients with Hughes Syndrome need. Coming from a patient, and coming straight from the heart, I believe that the lessons provided by this book are beyond value. - Munther A Khamashta MD FRCP Consultant Physician, Lupus Unit ST THOMAS' HOSPITAL, LONDON